cloud
VHP4Safety Cloud catalog
Below you find an overview of services available in the context of the VHP4Safety Platform. Additional services have been suggested and users can request additional services.
AOP-Wiki Snorql UI
Graphical interface to an AOP-Wiki SPARQL endpoint. [more info]
ArrayAnalysis
A user-friendly solutions for microarray quality control and pre-processing [more info]
BioModels
BioModels is a repository of mathematical models of biological and biomedical systems. [more info]
BioTransformer
Website with a tool that can predict metabolites for a SMILES. [more info]
BridgeDb
A framework to map identifiers between various biological databases and related sources. [more info]
CDK Depict
A webservice that converts a SMILES into 2D depictions (SVG or PNG). [more info]
CellDesigner
A modeling tool of biochemical networks. [more info]
CompTox
An online database to provide access to chemistry, toxicity, and exposure information for chemicals. [more info]
COPASI
Open-source software application for creating and solving mathematical models of biological processes such as metabolic networks, cell-signaling pathways, regulatory networks, infectious diseases, and many others. [more info]
cpLogD
A model to predict water–octanol distribution coefficient (logD) for chemical compounds. It is a proxy for the lipophilicity which is a major determinant of drug properties and overall suitability of drug candidates. [more info]
DECIMER
Online service to extract chemical structures from PDFs and images. [more info]
FAIRDOMHub
A web-accessible registry for storing, sharing and publishing research assets of biology projects. [more info]
Fairspace
An open source (meta)data platform that also allows import/export of metadata and uses RDF (turtle) underneath. [more info]
Flame
An open source framework for model development, hosting, and usage in production environments. [more info]
Joint Research Centre Data Catalogue
A catalogue of metadata records about datasets. [more info]
VHP4Safety Wikibase User Interface
A Synia-based graphical user interface to the content of the VHP4Safety Wikibase using SPARQL queries. [more info]
The OECD QSAR Toolbox
The OECD QSAR Toolbox is a software designed to support hazard assessment of chemicals as well as to increase mechanistic and other knowledge on chemical substances in a cost-efficient way. As a freely available computational tool, it promotes the use of assessment methods alternative to animals and minimizes unnecessary animal testing without reducing the safety of human health and environment. It is intended to be used by governments, chemical industry and other stakeholders. [more info]
OPSIN: Open Parser for Systematic IUPAC nomenclature
Website with a tool that can parse IUPAC names for chemicals into the chemical graph notation SMILES. [more info]
PopGen
Service to generate online virtual human population. [more info]
QSPRpred
Service to train and employ QSAR and PCM models. Takes a compound structure and pretrained model as input and returns the predicted potency of said compound. [more info]
SOM Prediction
A webservice for protein-structure and reactivity based (P450) site-of-metabolism prediction. [more info]
SysRev
Service to support literature research. [more info]
TXG-MAPr
An R-Shiny-based implementation of weighted gene co-expression network analysis (WGCNA) obtained from the Primary Human Hepatocytes (PHH) TG-GATEs dataset. [more info]
VHP4Safety Wikibase
A Wikibase instance to hold information about compounds. [more info]
WikiPathways - AOP Portal
This Adverse Outcome Pathway (AOP) portal for WikiPathways to highlight the molecular basis of AOPs or events in AOPs. [more info]
xploreaop
Shiny webapplication to visualize Adverse Outcome Pathway (AOP) networks. So far data has been included to interactively explore the AOPs for two liver outcomes: Cholestasis and Steatosis [more info]
Funding
VHP4Safety – the Virtual Human Platform for safety assessment project NWA 1292.19.272 is part of the NWA research program ‘Research along Routes by Consortia (ORC)’, which is funded by the Netherlands Organization for Scientific Research (NWO). The project started on June 1, 2021 with a budget of over 10 million Euros and will last for the duration of 5 years.